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Articles (64)
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A microfluidic culture platform for CNS axonal injury, regeneration and transport

Taylor, Anne M, Blurton-Jones, Mathew, Rhee, Seog Woo, Cribbs, David H, Cotman, Carl W, Jeon, Noo Li

Journal:

Nature Methods

Année:

2005

Langue:

english

Fichier:

PDF, 659 KB

english, 2005

Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss

Ager, Rahasson R., Davis, Joy L., Agazaryan, Andy, Benavente, Francisca, Poon, Wayne W., LaFerla, Frank M., Blurton-Jones, Mathew

Journal:

Hippocampus

Année:

2015

Langue:

english

Fichier:

PDF, 3.35 MB

english, 2015

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

Fiona E. McAlpine, Jae-Kyung Lee, Ashley S. Harms, Kelly A. Ruhn, Mathew Blurton-Jones, John Hong, Pritam Das, Todd E. Golde, Frank M. LaFerla, Salvatore Oddo, Armin Blesch, Malú G. Tansey

Journal:

Neurobiology of Disease

Année:

2009

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2009

CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer's disease

Shukla, Ankita K., McIntyre, Laura L., Marsh, Samuel E., Schneider, Christine A., Hoover, Evelyn M., Walsh, Craig M., Lodoen, Melissa B., Blurton-Jones, Mathew, Inlay, Matthew A.

Journal:

Glia

Année:

2018

Langue:

english

Fichier:

PDF, 2.86 MB

english, 2018

Microglia in Alzheimer's Disease: Exploring how Genetics and Phenotype Influence Risk

McQuade, Amanda, Blurton-Jones, Mathew

Journal:

Journal of Molecular Biology

Année:

2019

Langue:

english

Fichier:

PDF, 2.96 MB

english, 2019

Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions

Faal, Tannaz, Phan, Duc T.T., Davtyan, Hayk, Scarfone, Vanessa M., Varady, Erika, Blurton-Jones, Mathew, Hughes, Christopher C.W., Inlay, Matthew A.

Journal:

Stem Cell Reports

Année:

2019

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2019

Estrogen receptor immunoreactivity in the adult primate brain: Neuronal distribution and association with p75,trkA, and choline acetyltransferase

Blurton-Jones, M.M., Roberts, J.A., Tuszynski, M.H.

Journal:

The Journal of Comparative Neurology

Année:

1999

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1999

Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats

Mathew Blurton-Jones, Mark H. Tuszynski

Journal:

The Journal of Comparative Neurology

Année:

2002

Langue:

english

Fichier:

PDF, 6.00 MB

english, 2002

Anatomical evidence for transsynaptic influences of estrogen on brain-derived neurotrophic factor expression

M. Blurton-Jones, P.N. Kuan, M.H. Tuszynski

Journal:

The Journal of Comparative Neurology

Année:

2004

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2004

Reactive astrocytes express estrogen receptors in the injured primate brain

Mathew Blurton-Jones, Mark H. Tuszynski

Journal:

The Journal of Comparative Neurology

Année:

2001

Langue:

english

Fichier:

PDF, 1020 KB

english, 2001

Origin, migration and fate of newly generated neurons in the adult rodent piriform cortex

Lee A. Shapiro, Kwan L. Ng, Richard Kinyamu, Patricia Whitaker-Azmitia, Eldon E. Geisert, Mathew Blurton-Jones, Qun-Yong Zhou, Charles E. Ribak

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Année:

2007

Langue:

english

Fichier:

PDF, 858 KB

english, 2007

Swedish Alzheimer Mutation Induces Mitochondrial Dysfunction Mediated by HSP60 Mislocalization of Amyloid Precursor Protein (APP) and Beta-Amyloid

Walls, K. C., Coskun, P., Gallegos-Perez, J. L., Zadourian, N., Freude, K., Rasool, S., Blurton-Jones, M., Green, K. N., LaFerla, F. M.

Journal:

Journal of Biological Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 2.48 MB

english, 2012

Studies in mother-infant interactions: Edited by H. R. Schaffer. London: Academic Press (1977). Pp. 478. Price: £14·80

N. Blurton-Jones

Journal:

Animal Behaviour

Année:

1979

Langue:

english

Fichier:

PDF, 293 KB

english, 1979

Inflammatory changes parallel the early stages of Alzheimer disease

A. Parachikova, M.G. Agadjanyan, D.H. Cribbs, M. Blurton-Jones, V. Perreau, J. Rogers, T.G. Beach, C.W. Cotman

Journal:

Neurobiology of Aging

Année:

2007

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2007

Aβ inhibits the proteasome and enhances amyloid and tau accumulation

Bertrand P. Tseng, Kim N. Green, Julie L. Chan, Mathew Blurton-Jones, Frank M. LaFerla

Journal:

Neurobiology of Aging

Année:

2008

Langue:

english

Fichier:

PDF, 3.43 MB

english, 2008

β-Amyloid impairs axonal BDNF retrograde trafficking

Wayne W. Poon, Mathew Blurton-Jones, Christina H. Tu, Leila M. Feinberg, Meredith A. Chabrier, Joe W. Harris, Noo Li Jeon, Carl W. Cotman

Journal:

Neurobiology of Aging

Année:

2011

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2011

Caspase-Mediated Degeneration in Alzheimer's Disease

David H. Cribbs, Wayne W. Poon, Robert A. Rissman, Mathew Blurton-Jones

Journal:

The American Journal of Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 79 KB

english, 2004

Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β

Maya A. Koike, Kim N. Green, Mathew Blurton-Jones, Frank M. LaFerla

Journal:

The American Journal of Pathology

Année:

2010

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2010

Longitudinal Behavioral and 6-[18F]Fluoro-l-DOPA-PET Assessment in MPTP-Hemiparkinsonian Monkeys

William P. Melega, Michael J. Raleigh, David B. Stout, Antonio A. DeSalles, Simon R. Cherry, Matthew Blurton-Jones, Grenvill G. Morton, Sung-Cheng Huang, Michael E. Phelps

Journal:

Experimental Neurology

Année:

1996

Langue:

english

Fichier:

PDF, 195 KB

english, 1996

Soluble A Promotes Wild-Type Tau Pathology In Vivo

Chabrier, M. A., Blurton-Jones, M., Agazaryan, A. A., Nerhus, J. L., Martinez-Coria, H., LaFerla, F. M.

Journal:

Journal of Neuroscience

Année:

2012

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2012

Estradiol-induced modulation of estrogen receptor-β and GABA within the adult neocortex: A potential transsynaptic mechanism for estrogen modulation of BDNF

Mathew Blurton-Jones, Mark H. Tuszynski

Journal:

The Journal of Comparative Neurology

Année:

2006

Langue:

english

Fichier:

PDF, 5.23 MB

english, 2006

Using neural stem cells to promote plasticity and improve cognition in transgenic AD mice

Mathew Blurton-Jones, Masashi Kitazawa, Hilda Martinez-Coria, Nicholas A. Castello, Franz-Joseph Muller, Jeanne F. Loring, Wayne W. Poon, Kim Green, Frank M. LaFerla

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 43 KB

english, 2010

Patterns in the distribution, site structure and assemblage composition of Hadza kill-butchering sites

J.F. O'Connell, K. Hawkes, N.G. Blurton-Jones

Journal:

Journal of Archaeological Science

Année:

1992

Langue:

english

Fichier:

PDF, 5.09 MB

english, 1992

Concise Review: Can Stem Cells be Used to Treat or Model Alzheimer's Disease?

Chen, Wesley W., Blurton-Jones, Mathew

Journal:

STEM CELLS

Année:

2012

Langue:

english

Fichier:

PDF, 347 KB

english, 2012

Human neural stem cell transplantation results in memory improvement in a 3xTg Alzheimer's disease model mice

Ager, Rahasson, Blurton-Jones, Mathew, Davis, Joy, Agazaryan, Andranik, LaFerla, Frank

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 76 KB

english, 2012

Soluble Aβ promotes wild-type tau pathology in vivo

Chabrier, Meredith, Blurton-Jones, Mathew, Agazaryan, Andy, Nerhus, Joy, LaFerla, Frank, Coria, Hilda Martinez

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 54 KB

english, 2012

Early detection of Alzheimer's disease: Probing mitochondrial function in the periphery

Lakatos, Anita, Coskun, Pinar, Ho, Jestine, Smith, Ian, Potkin, Steven, Saykin, Andrew, Blurton-Jones, Mathew

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 48 KB

english, 2013

Neuronal-Specific Overexpression of a Mutant Valosin-Containing Protein Associated with IBMPFD Promotes Aberrant Ubiquitin and TDP-43 Accumulation and Cognitive Dysfunction in Transgenic Mice

Rodriguez-Ortiz, Carlos J., Hoshino, Hitomi, Cheng, David, Liu-Yescevitz, Liqun, Blurton-Jones, Mathew, Wolozin, Benjamin, LaFerla, Frank M., Kitazawa, Masashi

Journal:

The American Journal of Pathology

Année:

2013

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2013

Restoration of memory in mouse models of Alzheimer's disease and neuronal loss: A new paradigm using human neural stem cell therapy

Blurton-Jones, Mathew, Ager, Rahasson, Nerhus, Joy, Agazaryan, Andy, Huhn, Stephen, Capela, Alexandra, LaFerla, Frank

Journal:

Alzheimer's & Dementia

Année:

2012

Langue:

english

Fichier:

PDF, 82 KB

english, 2012

Soluble Amyloid Precursor Protein Induces Rapid Neural Differentiation of Human Embryonic Stem Cells

Freude, Kristine K., Penjwini, Mahmud, Davis, Joy L., LaFerla, Frank M., Blurton-Jones, Mathew

Journal:

Journal of Biological Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 5.56 MB

english, 2011

The Deer and the Tiger. A Study of Wildlife in Indiaby George B. Schaller

Review by: Nicholas Blurton-Jones

Journal:

Human Biology

Année:

1969

Langue:

english

Fichier:

PDF, 244 KB

english, 1969

Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models

Blurton-Jones, Mathew, Spencer, Brian, Michael, Sara, Castello, Nicholas A, Agazaryan, Andranik A, Davis, Joy L, Müller, Franz-Josef, Loring, Jeanne F, Masliah, Eliezer, LaFerla, Frank M

Journal:

Stem Cell Research & Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2014

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

Blurton-Jones, M., Kitazawa, M., Martinez-Coria, H., Castello, N. A., Muller, F.-J., Loring, J. F., Yamasaki, T. R., Poon, W. W., Green, K. N., LaFerla, F. M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 2.87 MB

english, 2009

Examining the mechanisms that link β-amyloid and α-synuclein pathologies

Samuel E Marsh,Mathew Blurton-Jones

Journal:

Alzheimer's Research & Therapy

Année:

2012

Langue:

english

Fichier:

PDF, 472 KB

english, 2012

Breeding the stump-tailed macaque, Macaca arctoides

Trollope, J., Blurton-Jones, N. G.

Journal:

Laboratory Animals

Année:

1970

Langue:

english

Fichier:

PDF, 2.74 MB

english, 1970

Synergistic Interactions between A , Tau, and -Synuclein: Acceleration of Neuropathology and Cognitive Decline

Clinton, L. K., Blurton-Jones, M., Myczek, K., Trojanowski, J. Q., LaFerla, F. M.

Journal:

Journal of Neuroscience

Année:

2010

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2010

Neural Stem Cells Improve Memory in an Inducible Mouse Model of Neuronal Loss

Yamasaki, T. R., Blurton-Jones, M., Morrissette, D. A., Kitazawa, M., Oddo, S., LaFerla, F. M.

Journal:

Journal of Neuroscience

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

Human Stem Cell Manual || Transplanting Stem Cells into the Brain

Blurton-Jones, Mathew

Année:

2012

Langue:

english

Fichier:

PDF, 812 KB

english, 2012

Pathways by Which Aβ Facilitates Tau Pathology

Blurton-Jones, Mathew, LaFerla, Frank

Journal:

Current Alzheimer Research

Année:

2006

Langue:

english

Fichier:

PDF, 367 KB

english, 2006

An Update on Estrogen: Higher Cognitive Function, Receptor Mapping, Neurotrophic Effects

Taber, Katherine H., Murphy, Diane D., Blurton-Jones, Mathew M., Hurley, Robin A.

Journal:

Journal of Neuropsychiatry

Année:

2001

Langue:

english

Fichier:

PDF, 22.23 MB

english, 2001

Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism

N. Goldberg, J. Caesar, A. Park, S. Sedgh, G. Finogenov, E. Masliah, J. Davis, M. Blurton-jones

Année:

2015

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2015

The Role of Caspase Cleavage of Tau in Alzheimer Disease Neuropathology

Cotman, Carl W., Poon, Wayne W., Rissman, Robert A., Blurton-Jones, Mathew

Journal:

Journal of Neuropathology and Experimental Neurology

Année:

2005

Langue:

english

Fichier:

PDF, 598 KB

english, 2005

BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens

White, André O., Kramár, Enikö A., López, Alberto J., Kwapis, Janine L., Doan, John, Saldana, David, Davatolhagh, M. Felicia, Alaghband, Yasaman, Blurton-Jones, Mathew, Matheos, Dina P., Wood, Marcelo

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2016

DEVELOPMENT OF IPSC-BASED BIOMARKERS TO IDENTIFY THE PATIENT POPULATION RESPONSIVE TO ALLOPREGNANOLONE

Solinsky, Christine M., Hennes, Valerie, Blurton-Jones, Mathew, Park, Jenny Ayoung, Chui, Helena C., Ichida, Justin K., Brinton, Roberta Diaz

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 55 KB

english, 2016

THE FIRST MULTITEP-BASED DNA VACCINE TARGETING N-TERMINUS OF PATHOLOGICAL TAU INDUCES STRONG IMMUNE RESPONSES AND REDUCES TAU PATHOLOGY IN TAU TRANSGENIC MICE

Davtyan, Hayk, Chen, Wesley W., Zagorski, Karen, Davis, Joy, Petrushina, Irina, Cribbs, David H., Agadjanyan, Michael G., Blurton-Jones, Mathew, Ghochikyan, Anahit

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 48 KB

english, 2016

HUMANIZED MAB, ARMANEZUMAB TARGETING N-TERMINUS OF PATHOLOGICAL TAU: CHARACTERIZATION AND THERAPEUTIC POTENCY

Ghochikyan, Anahit, Zagorski, Karen, Kazarian, Konstantin, Davtyan, Hayk, Petrushina, Irina, Davis, Joy, Chen, Wesley W., Antonenko, Maxim, Blurton-Jones, Mathew, Cribbs, David H., Agadjanyan, Michael

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 50 KB

english, 2016

HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease

Marsh, Samuel E., Yeung, Stephen T., Torres, Maria, Lau, Lydia, Davis, Joy L., Monuki, Edwin S., Poon, Wayne W., Blurton-Jones, Mathew

Journal:

Stem Cell Reports

Année:

2017

Langue:

english

Fichier:

PDF, 4.01 MB

english, 2017

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Goldberg, Natalie R.S., Marsh, Samuel E., Ochaba, Joseph, Shelley, Brandon C., Davtyan, Hayk, Thompson, Leslie M., Steffan, Joan S., Svendsen, Clive N., Blurton-Jones, Mathew

Journal:

Stem Cells Translational Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2017

Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support

Marsh, Samuel E., Blurton-Jones, Mathew

Journal:

Neurochemistry International

Année:

2017

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2017

Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice

Lakatos, Anita, Goldberg, Natalie R. S., Blurton-Jones, Mathew

Journal:

Acta Neuropathologica Communications

Année:

2017

Langue:

english

Fichier:

PDF, 3.74 MB

english, 2017